Biosensors: a Sensitive Strategy to Detect Glucose in Body Fluids

Over the past decades diabetes is one of the leading causes of mortality and morbidity in the world, thus inventing glucose biosensors with accurate continuous monitoring is of growing concern amongst the scientists worldwide. This manuscript reviews the development of glucose biosensors over the last 50 years since the invention of the first glucose sensing electrode and various approaches considered to develop accurate and modern techniques of glucose sensing. This review provides brief introduction to principles of various glucose biosensors with systemization and classification of glucose monitoring principles. Thus the main aim of this manuscript is to check history of glucose biosensors, comment on their current status and commercial aspects, and examine future challenges.